相互作用
Tetracycline + Typhoid vaccine live
重症度: 重大
Tetracycline and Typhoid vaccine live: major interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Oral live attenuated typhoid vaccine (Ty21a) is a viable bacterial strain that antibiotics can inactivate, reducing the immune response and protection. Tetracyclines are active against Salmonella, so vaccine failure is possible.
この相互作用をわかりやすく説明すると
Tetracycline and Typhoid vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Antibacterial activity kills or inhibits the live attenuated Salmonella strain, reducing colonisation and immunogenicity.
対処法
Avoid antibiotics from at least 3 days before until after completing the vaccine course, per labeling. If antibiotics are required, delay vaccination or use the inactivated injectable vaccine.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、TetracyclineとTyphoid vaccine liveの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Tetracyclineのその他の相互作用
よくある質問
Can I take Tetracycline with Typhoid vaccine live?
MediHelp rates the interaction as major. Tetracycline and Typhoid vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oral live attenuated typhoid vaccine (Ty21a) is a viable bacterial strain that antibiotics can inactivate, reducing the immune response and protection. Tetracyclines are active against Salmonella, so vaccine failure is possible.
How serious is the interaction between Tetracycline and Typhoid vaccine live?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid antibiotics from at least 3 days before until after completing the vaccine course, per labeling. If antibiotics are required, delay vaccination or use the inactivated injectable vaccine.
What other medicines interact with Tetracycline?
MediHelp also lists interactions of Tetracycline with, for example, Acitretin, Methoxyflurane, Isotretinoin. The full list is on the Tetracycline page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
