Referência de medicamentos
Coagulation factor x
Coagulation factor x is a medicine in the class miscellaneous.
- Classe do medicamento: Miscellaneous
Última atualização Fontes: US FDA label
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Pontos-chave
- Classe do medicamento
- Miscellaneous
- Código ATC
- B02BD13
- Nomes comerciais
- 1
- Países e mercados
- 1
Como funciona
Temporarily replaces the missing Factor X needed for effective hemostasis. Factor X is activated to Factor Xa, which with Factor Va forms the prothrombinase complex that converts prothrombin to thrombin, leading to a cross-linked fibrin clot.
Dose habitual em adultos (resumo da bula)
Routine prophylaxis of bleeding episodes (adults and adolescents 12 years or older): 25 IU/kg IV twice weekly; adjust to clinical response; do not administer more than 60 IU/kg daily
Gravidez e amamentação
- Gravidez
- Unknown Limited human data and no animal studies. Factor X deficiency itself raises the risk of bleeding and miscarriage, so use when clearly needed under a specialist.
- Amamentação
- Unknown No data on milk levels or effects on the infant. A large plasma protein, unlikely to be absorbed by the infant. Weigh the benefits of breastfeeding against the mother's need for treatment.
Efeitos adversos relatados
- Infusion site erythema
- Infusion site pain
- Fatigue
- Back pain
Contraindicações
- Life-threatening hypersensitivity reactions to COAGADEX
Quem deve ter cuidado
- Hypersensitivity reactions including anaphylaxis are possible; discontinue and treat if symptoms occur
- Neutralizing antibodies (inhibitors) may develop; if expected Factor X levels are not attained or bleeding is uncontrolled, assay for inhibitor
- Made from human blood; may transmit infectious agents including viruses and vCJD/CJD agents
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- IV preparation and dilution
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Outros medicamentos desta classe
Perguntas frequentes
What is Coagulation factor x used for?
Coagulation factor x is a medicine in the class miscellaneous.
What side effects have been reported with Coagulation factor x?
Infusion site erythema, Infusion site pain, Fatigue, Back pain.
Can Coagulation factor x be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Limited human data and no animal studies. Factor X deficiency itself raises the risk of bleeding and miscarriage, so use when clearly needed under a specialist. Breastfeeding: Unknown. No data on milk levels or effects on the infant. A large plasma protein, unlikely to be absorbed by the infant. Weigh the benefits of breastfeeding against the mother's need for treatment.
What does Coagulation factor x interact with?
MediHelp does not list a checked interaction for Coagulation factor x yet. Always tell your pharmacist about every medicine you take.
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