Referência de medicamentos
Pitavastatin
Pitavastatin is a medicine in the class cardiovascular. It is used for dyslipidemia.
- Classe do medicamento: Cardiovascular
- Indicado para: dyslipidemia
Última atualização
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O conteúdo clínico desta página está disponível apenas em inglês.
Pontos-chave
- Classe do medicamento
- Cardiovascular
- Formas farmacêuticas comuns
- comprimido
- Concentrações comuns
- 2 mg, 4 mg, 1 mg
- Interações conhecidas
- 82 (Contraindicada: 2 · Grave: 11 · Moderada: 45 · Leve: 24)
- Nomes comerciais
- 24
- Países e mercados
- 4
Para que é usado
Como funciona
HMG-CoA reductase inhibitor, inhibits rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase
Dose habitual em adultos (resumo da bula)
Hyperlipidemia: Recommended starting dose: 2 mg PO qDay May increase to 4 mg PO qDay if necessary
Como costuma ser tomado
Statins are taken by mouth once a day, long term, with blood tests to check the response and liver function.
Gravidez e amamentação
- Gravidez
- Unsafe EU labels contraindicate it in pregnancy and in women not using contraception (reduced fetal cholesterol synthesis); stop 1 month before conceiving. US label (2026) no longer does: stop when pregnancy is recognised unless the need is compelling; statin data show no rise in birth defects.
- Amamentação
- Unsafe Not known if it passes into human milk; it passes into rat milk and is 99% protein bound. EU label: contraindicated; US label: not recommended (possible effects on infant lipid metabolism). LactMed: consensus is not to use it; some experts consider pravastatin or rosuvastatin lower risk. Avoid.
Efeitos adversos relatados
- Diarrhea
- Constipation
- Back pain
- Myalgia
- Pain in extremity
Quem deve ter cuidado
- Increased serum transaminases reported; typically, elevations are transient and either resolved or improved on continued therapy or after briefly interrupting therapy
- Myopathy risk factors include: age ≥65 yr, uncontrolled hypothyroidism, renal impairment, coadministration of drugs that decrease statin clearance or add to myopathy risk
- Contraindicated: Coadministration with cyclosporine
Unexplained muscle pain, tenderness or weakness while taking a statin should be reported promptly. Statins are not used in pregnancy, and some other medicines raise their levels and risk.
Informe ao farmacêutico ou ao médico sobre gravidez ou amamentação, doença renal ou hepática, alergias e todos os outros medicamentos ou suplementos que você usa.
Principais interações (82)
- Cyclosporin + Pitavastatin Contraindicated
- Cyclosporine + Pitavastatin Contraindicated
- Erythromycin + Pitavastatin Major
- Erythromycin base + Pitavastatin Major
- Erythromycin ethylsuccinate + Pitavastatin Major
- Erythromycin lactobionate + Pitavastatin Major
- Erythromycin stearate + Pitavastatin Major
- Gemfibrozil + Pitavastatin Major
- Glecaprevir / pibrentasvir + Pitavastatin Major
- Letermovir + Pitavastatin Major
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- Dosing by age, kidney and liver function, and further dose lines
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- Patient counselling points
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Outros medicamentos desta classe
Perguntas frequentes
What is Pitavastatin used for?
Pitavastatin is a medicine in the class cardiovascular. It is used for Dyslipidemia, Hypercholesterolemia.
What side effects have been reported with Pitavastatin?
Diarrhea, Constipation, Back pain, Myalgia, Pain in extremity.
Can Pitavastatin be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. EU labels contraindicate it in pregnancy and in women not using contraception (reduced fetal cholesterol synthesis); stop 1 month before conceiving. US label (2026) no longer does: stop when pregnancy is recognised unless the need is compelling; statin data show no rise in birth defects. Breastfeeding: Unsafe. Not known if it passes into human milk; it passes into rat milk and is 99% protein bound. EU label: contraindicated; US label: not recommended (possible effects on infant lipid metabolism). LactMed: consensus is not to use it; some experts consider pravastatin or rosuvastatin lower risk. Avoid.
What does Pitavastatin interact with?
MediHelp lists 82 known interactions for Pitavastatin. Contraindicated: 2 · Major: 11 · Moderate: 45 · Minor: 24. The most serious include Cyclosporin, Cyclosporine, Erythromycin.
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