Referência de medicamentos
Risankizumab
Risankizumab is a medicine in the class miscellaneous. It is used for crohn's disease.
- Classe do medicamento: Miscellaneous
- Indicado para: crohn's disease
Última atualização Fontes: US FDA label
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Pontos-chave
- Classe do medicamento
- Miscellaneous
- Código ATC
- L04AC18
- Formas farmacêuticas comuns
- injeção
- Concentrações comuns
- 150 mg/ml
- Interações conhecidas
- 2 (Grave: 1 · Moderada: 1)
- Nomes comerciais
- 3
- Países e mercados
- 3
Para que é usado
Como funciona
Humanized IgG1 monoclonal antibody that selectively binds the p19 subunit of human IL-23 and inhibits its interaction with the IL-23 receptor, reducing release of pro-inflammatory cytokines and chemokines.
Dose habitual em adultos (resumo da bula)
Plaque psoriasis: 150 mg, subcutaneous injection, at Week 0, Week 4, and every 12 weeks thereafter
Gravidez e amamentação
- Gravidez
- Unknown Data are insufficient to show a risk; a registry exists. Antibodies cross the placenta, mainly late in pregnancy, and may suppress the infant's immunity. Monkeys had more fetal and infant deaths at high doses. Use only if needed; delay live vaccines in exposed infants.
- Amamentação
- Safe No human milk data. A large antibody: milk levels are likely very low and it is probably digested in the infant's gut. Some expert guidelines consider it acceptable while breastfeeding (LactMed). US label: weigh benefits.
Efeitos adversos relatados
- Upper respiratory infections
- Headache
- Fatigue
- Injection site reactions
- Tinea infections
- Arthralgia
Contraindicações
- History of serious hypersensitivity reaction to risankizumab-rzaa or any excipients.
Quem deve ter cuidado
- Serious hypersensitivity reactions including anaphylaxis may occur; discontinue and treat immediately if it occurs.
- May increase risk of infection; do not start in clinically important active infection and withhold if one develops until resolved.
- Evaluate for TB before initiating; do not give to patients with active TB; monitor for TB signs during and after treatment.
Informe ao farmacêutico ou ao médico sobre gravidez ou amamentação, doença renal ou hepática, alergias e todos os outros medicamentos ou suplementos que você usa.
Principais interações (2)
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para abrir a monografia completa de Risankizumab: doses, gravidez e amamentação, efeitos adversos, advertências e todas as interações.
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- IV preparation and dilution
Experimente o Pro+ grátis por 7 dias na web. Sem cartão.
Outros medicamentos desta classe
Leituras rápidas relacionadas
Perguntas frequentes
What is Risankizumab used for?
Risankizumab is a medicine in the class miscellaneous. It is used for Crohn's disease, Plaque psoriasis, Psoriatic arthritis, Ulcerative colitis.
What side effects have been reported with Risankizumab?
Upper respiratory infections, Headache, Fatigue, Injection site reactions, Tinea infections, Arthralgia.
Can Risankizumab be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Data are insufficient to show a risk; a registry exists. Antibodies cross the placenta, mainly late in pregnancy, and may suppress the infant's immunity. Monkeys had more fetal and infant deaths at high doses. Use only if needed; delay live vaccines in exposed infants. Breastfeeding: Safe. No human milk data. A large antibody: milk levels are likely very low and it is probably digested in the infant's gut. Some expert guidelines consider it acceptable while breastfeeding (LactMed). US label: weigh benefits.
What does Risankizumab interact with?
MediHelp lists 2 known interactions for Risankizumab. Major: 1 · Moderate: 1. The most serious include Upadacitinib, Measles mumps and rubella vaccine.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
