Interações medicamentosas
Abciximab + Ticagrelor
Gravidade: Grave
Abciximab and Ticagrelor: major interaction.
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Resumo
Ticagrelor with a glycoprotein IIb/IIIa inhibitor produces strong combined platelet inhibition and increases the risk of major bleeding. This pairing is sometimes used deliberately during PCI but requires care.
O que esta interação significa em palavras simples
Abciximab and Ticagrelor can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Abciximab belongs to Cardiovascular; Ticagrelor belongs to Cardiovascular.
Por que acontece
Additive antiplatelet effects via P2Y12 blockade and GP IIb/IIIa receptor blockade.
O que fazer
Use only when clearly indicated, such as during PCI, and monitor hemoglobin, platelet count and bleeding signs. Limit duration of the GP IIb/IIIa infusion.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Ticagrelor
- Itraconazole + Ticagrelor Contraindicada
- Ketoconazole + Ticagrelor Contraindicada
- Levoketoconazole + Ticagrelor Contraindicada
- Abrocitinib + Ticagrelor Grave
- Acalabrutinib + Ticagrelor Grave
- Acetylsalicylic acid + Ticagrelor Grave
Outras interações de Abciximab
Perguntas frequentes
Can I take Abciximab with Ticagrelor?
MediHelp rates the interaction as major. Abciximab and Ticagrelor can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ticagrelor with a glycoprotein IIb/IIIa inhibitor produces strong combined platelet inhibition and increases the risk of major bleeding. This pairing is sometimes used deliberately during PCI but requires care.
How serious is the interaction between Abciximab and Ticagrelor?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only when clearly indicated, such as during PCI, and monitor hemoglobin, platelet count and bleeding signs. Limit duration of the GP IIb/IIIa infusion.
What other medicines interact with Ticagrelor?
MediHelp also lists interactions of Ticagrelor with, for example, Itraconazole, Ketoconazole, Levoketoconazole. The full list is on the Ticagrelor page.
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