Interações medicamentosas
Acalabrutinib + Ticagrelor
Gravidade: Grave
Acalabrutinib and Ticagrelor: major interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Acalabrutinib impairs platelet function and is associated with bleeding and hemorrhage. Adding ticagrelor, a potent P2Y12 inhibitor, further raises bleeding risk including serious events.
O que esta interação significa em palavras simples
Acalabrutinib and Ticagrelor can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Acalabrutinib belongs to Oncology; Ticagrelor belongs to Cardiovascular.
Por que acontece
Additive platelet inhibition from BTK inhibition and P2Y12 receptor blockade.
O que fazer
Monitor for bleeding and weigh the necessity of combined therapy. Consider holding acalabrutinib around surgery as per labeling.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Acalabrutinib e Ticagrelor, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 7 dias na web. Sem cartão.
Outras interações de Ticagrelor
- Itraconazole + Ticagrelor Contraindicada
- Ketoconazole + Ticagrelor Contraindicada
- Levoketoconazole + Ticagrelor Contraindicada
- Abciximab + Ticagrelor Grave
- Abrocitinib + Ticagrelor Grave
- Acetylsalicylic acid + Ticagrelor Grave
Outras interações de Acalabrutinib
Perguntas frequentes
Can I take Acalabrutinib with Ticagrelor?
MediHelp rates the interaction as major. Acalabrutinib and Ticagrelor can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Acalabrutinib impairs platelet function and is associated with bleeding and hemorrhage. Adding ticagrelor, a potent P2Y12 inhibitor, further raises bleeding risk including serious events.
How serious is the interaction between Acalabrutinib and Ticagrelor?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding and weigh the necessity of combined therapy. Consider holding acalabrutinib around surgery as per labeling.
What other medicines interact with Ticagrelor?
MediHelp also lists interactions of Ticagrelor with, for example, Itraconazole, Ketoconazole, Levoketoconazole. The full list is on the Ticagrelor page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
