Interações medicamentosas
Aluminum hydroxide + Omadacycline
Gravidade: Moderada
Aluminum hydroxide and Omadacycline: moderate interaction.
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Resumo
Aluminum binds omadacycline in the gut and reduces its absorption. This may reduce antibacterial efficacy.
O que esta interação significa em palavras simples
Aluminum hydroxide and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Omadacycline belongs to Anti Bacterial.
Por que acontece
Chelation of the tetracycline by polyvalent aluminum cations forms poorly absorbed complexes.
O que fazer
Separate dosing; take omadacycline at least 4 hours before or 2 hours after antacids, per labeling. Monitor clinical response.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Aluminum hydroxide
Outras interações de Omadacycline
- Acitretin + Omadacycline Contraindicada
- Isotretinoin + Omadacycline Grave
- Omadacycline + Tretinoin Grave
- Amoxicillin-clavulanic acid + Omadacycline Moderada
- Amoxicillin + Omadacycline Moderada
- Ampicillin-sulbactam + Omadacycline Moderada
Perguntas frequentes
Can I take Aluminum hydroxide with Omadacycline?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aluminum binds omadacycline in the gut and reduces its absorption. This may reduce antibacterial efficacy.
How serious is the interaction between Aluminum hydroxide and Omadacycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate dosing; take omadacycline at least 4 hours before or 2 hours after antacids, per labeling. Monitor clinical response.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
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