Interações medicamentosas
Aluminum hydroxide + Vitamin d
Gravidade: Grave
Aluminum hydroxide and Vitamin d: major interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Vitamin D and its analogues increase intestinal absorption of aluminum from aluminum-containing antacids. With long-term use, especially in renal impairment, aluminum may accumulate and cause bone disease, anemia or neurotoxicity.
O que esta interação significa em palavras simples
Aluminum hydroxide and Vitamin d can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Aluminum hydroxide belongs to Gastrointestinal Tract; Vitamin d belongs to Gastrointestinal Tract.
Por que acontece
Vitamin D enhances intestinal absorption of aluminum, and impaired renal excretion allows tissue accumulation.
O que fazer
Avoid chronic aluminum antacids in patients taking vitamin D, particularly with chronic kidney disease. Use a non-aluminum alternative and monitor serum aluminum if exposure is unavoidable.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Aluminum hydroxide
Outras interações de Vitamin d
Perguntas frequentes
Can I take Aluminum hydroxide with Vitamin d?
MediHelp rates the interaction as major. Aluminum hydroxide and Vitamin d can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Vitamin D and its analogues increase intestinal absorption of aluminum from aluminum-containing antacids. With long-term use, especially in renal impairment, aluminum may accumulate and cause bone disease, anemia or neurotoxicity.
How serious is the interaction between Aluminum hydroxide and Vitamin d?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid chronic aluminum antacids in patients taking vitamin D, particularly with chronic kidney disease. Use a non-aluminum alternative and monitor serum aluminum if exposure is unavoidable.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
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