Interações medicamentosas
Amoxicillin-clavulanic acid + Omadacycline
Gravidade: Moderada
Amoxicillin-clavulanic acid and Omadacycline: moderate interaction.
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Resumo
Omadacycline is a bacteriostatic tetracycline that may theoretically blunt penicillin bactericidal effects. There is limited clinical evidence of harm. Relevance is greatest in serious infections.
O que esta interação significa em palavras simples
Amoxicillin-clavulanic acid and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amoxicillin-clavulanic acid belongs to Anti Bacterial; Omadacycline belongs to Anti Bacterial.
Por que acontece
Pharmacodynamic antagonism: inhibition of bacterial growth reduces the activity of beta-lactams that act on dividing cells.
O que fazer
Avoid combining for severe infections unless dual therapy is clearly justified. Monitor clinical response if used together.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Amoxicillin-clavulanic acid
- Amoxicillin-clavulanic acid + Methotrexate Grave
- Amoxicillin-clavulanic acid + Pexidartinib Grave
- Amoxicillin-clavulanic acid + Pretomanid Grave
- Allopurinol + Amoxicillin-clavulanic acid Moderada
- Amoxicillin-clavulanic acid + Bcg vaccine live Moderada
- Amoxicillin-clavulanic acid + Chloramphenicol Moderada
Outras interações de Omadacycline
- Acitretin + Omadacycline Contraindicada
- Isotretinoin + Omadacycline Grave
- Omadacycline + Tretinoin Grave
- Aluminum hydroxide + Omadacycline Moderada
- Amoxicillin + Omadacycline Moderada
- Ampicillin-sulbactam + Omadacycline Moderada
Perguntas frequentes
Can I take Amoxicillin-clavulanic acid with Omadacycline?
MediHelp rates the interaction as moderate. Amoxicillin-clavulanic acid and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Omadacycline is a bacteriostatic tetracycline that may theoretically blunt penicillin bactericidal effects. There is limited clinical evidence of harm. Relevance is greatest in serious infections.
How serious is the interaction between Amoxicillin-clavulanic acid and Omadacycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining for severe infections unless dual therapy is clearly justified. Monitor clinical response if used together.
What other medicines interact with Amoxicillin-clavulanic acid?
MediHelp also lists interactions of Amoxicillin-clavulanic acid with, for example, Methotrexate, Pexidartinib, Pretomanid. The full list is on the Amoxicillin-clavulanic acid page.
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