Interações medicamentosas
Aluminum hydroxide / magnesium trisilicate + Ethambutol
Gravidade: Moderada
Aluminum hydroxide / magnesium trisilicate and Ethambutol: moderate interaction.
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Resumo
Aluminium-containing antacids can reduce ethambutol absorption, which may lower its blood levels and weaken antimycobacterial effect. The effect is predicted rather than firmly established.
O que esta interação significa em palavras simples
Aluminum hydroxide / magnesium trisilicate and Ethambutol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Aluminium and magnesium cations may bind ethambutol in the gut or alter gastric conditions, reducing absorption.
O que fazer
Give ethambutol at least 4 hours before aluminium-containing antacids. Monitor treatment response.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Ethambutol
- Allopurinol + Ethambutol Moderada
- Aluminum hydroxide / magnesium carbonate + Ethambutol Moderada
- Bcg vaccine live + Ethambutol Moderada
- Ethambutol + Febuxostat Moderada
- Ethambutol + Probenecid Moderada
- Aluminum hydroxide + Ethambutol Leve
Perguntas frequentes
Can I take Aluminum hydroxide / magnesium trisilicate with Ethambutol?
MediHelp rates the interaction as moderate. Aluminum hydroxide / magnesium trisilicate and Ethambutol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aluminium-containing antacids can reduce ethambutol absorption, which may lower its blood levels and weaken antimycobacterial effect. The effect is predicted rather than firmly established.
How serious is the interaction between Aluminum hydroxide / magnesium trisilicate and Ethambutol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give ethambutol at least 4 hours before aluminium-containing antacids. Monitor treatment response.
What other medicines interact with Ethambutol?
MediHelp also lists interactions of Ethambutol with, for example, Allopurinol, Aluminum hydroxide / magnesium carbonate, Bcg vaccine live. The full list is on the Ethambutol page.
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