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Interações medicamentosas

Bcg vaccine live + Ethambutol

Gravidade: Moderada

Bcg vaccine live and Ethambutol: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Ethambutol is active against mycobacteria and could reduce replication of the live BCG strain, potentially lowering vaccine effect. The interaction is largely theoretical, as antimycobacterial drugs generally impair live BCG.

O que esta interação significa em palavras simples

Bcg vaccine live and Ethambutol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Nível de evidência: Low

Por que acontece

Antimycobacterial activity of ethambutol may inhibit the live attenuated BCG organism.

O que fazer

Avoid giving BCG vaccine during ethambutol therapy; defer vaccination until after the course is finished.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Bcg vaccine live with Ethambutol?

MediHelp rates the interaction as moderate. Bcg vaccine live and Ethambutol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ethambutol is active against mycobacteria and could reduce replication of the live BCG strain, potentially lowering vaccine effect. The interaction is largely theoretical, as antimycobacterial drugs generally impair live BCG.

How serious is the interaction between Bcg vaccine live and Ethambutol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving BCG vaccine during ethambutol therapy; defer vaccination until after the course is finished.

What other medicines interact with Ethambutol?

MediHelp also lists interactions of Ethambutol with, for example, Allopurinol, Aluminum hydroxide / magnesium carbonate, Aluminum hydroxide / magnesium trisilicate. The full list is on the Ethambutol page.

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