Interações medicamentosas
Amlodipine-benazepril + Canagliflozin
Gravidade: Moderada
Amlodipine-benazepril and Canagliflozin: moderate interaction.
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Resumo
Canagliflozin does not typically raise potassium in the way potassium-sparing agents do, and it may even lower hyperkalemia risk. The more relevant concern is additive volume depletion and hypotension with benazepril, with possible effects on renal function.
O que esta interação significa em palavras simples
Amlodipine-benazepril and Canagliflozin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-benazepril belongs to Cardiovascular; Canagliflozin belongs to Endocrine.
Por que acontece
Additive hypotensive and volume-depleting effects from osmotic diuresis plus RAAS inhibition.
O que fazer
Assess volume status and monitor blood pressure, creatinine and potassium after starting canagliflozin. Reduce diuretic or antihypertensive doses if hypovolemia develops.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicada
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicada
- Aldesleukin + Amlodipine-benazepril Grave
- Amifostine + Amlodipine-benazepril Grave
- Amiloride + Amlodipine-benazepril Grave
- Amlodipine-benazepril + Azilsartan Grave
Outras interações de Canagliflozin
Perguntas frequentes
Can I take Amlodipine-benazepril with Canagliflozin?
MediHelp rates the interaction as moderate. Amlodipine-benazepril and Canagliflozin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Canagliflozin does not typically raise potassium in the way potassium-sparing agents do, and it may even lower hyperkalemia risk. The more relevant concern is additive volume depletion and hypotension with benazepril, with possible effects on renal function.
How serious is the interaction between Amlodipine-benazepril and Canagliflozin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Assess volume status and monitor blood pressure, creatinine and potassium after starting canagliflozin. Reduce diuretic or antihypertensive doses if hypovolemia develops.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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