Interações medicamentosas
Amlodipine-hydrochlorothiazide-valsartan + Corticotropin
Gravidade: Moderada
Amlodipine-hydrochlorothiazide-valsartan and Corticotropin: moderate interaction.
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Resumo
Corticotropin stimulates adrenal corticosteroid production, which promotes potassium loss and sodium retention. With hydrochlorothiazide this can worsen hypokalemia and reduce blood pressure control.
O que esta interação significa em palavras simples
Amlodipine-hydrochlorothiazide-valsartan and Corticotropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-hydrochlorothiazide-valsartan belongs to Cardiovascular; Corticotropin belongs to Endocrine.
Por que acontece
Additive renal potassium wasting from thiazide and corticotropin-induced mineralocorticoid and glucocorticoid effects.
O que fazer
Monitor serum potassium and blood pressure during therapy and supplement potassium if needed.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Amlodipine-hydrochlorothiazide-valsartan
- Aliskiren + Amlodipine-hydrochlorothiazide-valsartan Contraindicada
- Amlodipine-hydrochlorothiazide-valsartan + Dofetilide Contraindicada
- Amlodipine-hydrochlorothiazide-valsartan + Sparsentan Contraindicada
- Aceclofenac + Amlodipine-hydrochlorothiazide-valsartan Grave
- Aldesleukin + Amlodipine-hydrochlorothiazide-valsartan Grave
- Amifostine + Amlodipine-hydrochlorothiazide-valsartan Grave
Outras interações de Corticotropin
Perguntas frequentes
Can I take Amlodipine-hydrochlorothiazide-valsartan with Corticotropin?
MediHelp rates the interaction as moderate. Amlodipine-hydrochlorothiazide-valsartan and Corticotropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Corticotropin stimulates adrenal corticosteroid production, which promotes potassium loss and sodium retention. With hydrochlorothiazide this can worsen hypokalemia and reduce blood pressure control.
How serious is the interaction between Amlodipine-hydrochlorothiazide-valsartan and Corticotropin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and blood pressure during therapy and supplement potassium if needed.
What other medicines interact with Amlodipine-hydrochlorothiazide-valsartan?
MediHelp also lists interactions of Amlodipine-hydrochlorothiazide-valsartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-hydrochlorothiazide-valsartan page.
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