Interações medicamentosas
Ampicillin-sulbactam + Bcg vaccine live
Gravidade: Moderada
Ampicillin-sulbactam and Bcg vaccine live: moderate interaction.
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Resumo
Live BCG contains viable bacteria, and antibiotics active against them can reduce vaccine take. Ampicillin has limited activity against BCG, but the labeling for live bacterial vaccines advises avoiding concurrent antibiotics.
O que esta interação significa em palavras simples
Ampicillin-sulbactam and Bcg vaccine live can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Antibacterial activity may reduce replication of the live vaccine organism, lessening the immune response.
O que fazer
Defer BCG vaccination until antibiotic therapy is complete, where the vaccine is not urgent.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Ampicillin-sulbactam
Perguntas frequentes
Can I take Ampicillin-sulbactam with Bcg vaccine live?
MediHelp rates the interaction as moderate. Ampicillin-sulbactam and Bcg vaccine live can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Live BCG contains viable bacteria, and antibiotics active against them can reduce vaccine take. Ampicillin has limited activity against BCG, but the labeling for live bacterial vaccines advises avoiding concurrent antibiotics.
How serious is the interaction between Ampicillin-sulbactam and Bcg vaccine live?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Defer BCG vaccination until antibiotic therapy is complete, where the vaccine is not urgent.
What other medicines interact with Ampicillin-sulbactam?
MediHelp also lists interactions of Ampicillin-sulbactam with, for example, Methotrexate, Allopurinol, Chloramphenicol. The full list is on the Ampicillin-sulbactam page.
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