Interações medicamentosas
Ampicillin-sulbactam + Cholera vaccine
Gravidade: Moderada
Ampicillin-sulbactam and Cholera vaccine: moderate interaction.
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Resumo
Oral live attenuated cholera vaccine contains a living bacterial strain that antibiotics can kill. Recent antibiotic exposure may therefore reduce vaccine take and protection.
O que esta interação significa em palavras simples
Ampicillin-sulbactam and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Antibacterial activity against the live attenuated vaccine strain impairs colonisation and immune response.
O que fazer
Do not give the vaccine within 14 days after systemic antibiotics. Delay vaccination until the interval has passed.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Ampicillin-sulbactam
Perguntas frequentes
Can I take Ampicillin-sulbactam with Cholera vaccine?
MediHelp rates the interaction as moderate. Ampicillin-sulbactam and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral live attenuated cholera vaccine contains a living bacterial strain that antibiotics can kill. Recent antibiotic exposure may therefore reduce vaccine take and protection.
How serious is the interaction between Ampicillin-sulbactam and Cholera vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the vaccine within 14 days after systemic antibiotics. Delay vaccination until the interval has passed.
What other medicines interact with Ampicillin-sulbactam?
MediHelp also lists interactions of Ampicillin-sulbactam with, for example, Methotrexate, Allopurinol, Bcg vaccine live. The full list is on the Ampicillin-sulbactam page.
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