Pular para o conteúdo

Interações medicamentosas

Anagrelide + Panobinostat

Gravidade: Contraindicada

Anagrelide and Panobinostat: contraindicated interaction.

Última atualização

Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Panobinostat markedly prolongs the QT interval, and its labeling advises against use with other QT-prolonging drugs. Adding anagrelide raises the risk of torsades de pointes and sudden death.

O que esta interação significa em palavras simples

Anagrelide and Panobinostat are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Anagrelide belongs to Cardiovascular; Panobinostat belongs to Oncology.

Nível de evidência: Moderate

Por que acontece

Additive pharmacodynamic QT prolongation.

O que fazer

Do not combine; select an alternative to anagrelide during panobinostat therapy. Monitor ECG and electrolytes per panobinostat labeling.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Para assinantes do Pro+

Desbloqueie a página completa

Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Anagrelide e Panobinostat, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Experimente o Pro+ grátis por 14 dias na web. Sem cartão.

Perguntas frequentes

Can I take Anagrelide with Panobinostat?

MediHelp rates the interaction as contraindicated. Anagrelide and Panobinostat are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Panobinostat markedly prolongs the QT interval, and its labeling advises against use with other QT-prolonging drugs. Adding anagrelide raises the risk of torsades de pointes and sudden death.

How serious is the interaction between Anagrelide and Panobinostat?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; select an alternative to anagrelide during panobinostat therapy. Monitor ECG and electrolytes per panobinostat labeling.

What other medicines interact with Anagrelide?

MediHelp also lists interactions of Anagrelide with, for example, Pimozide, Thioridazine, Vandetanib. The full list is on the Anagrelide page.

Monografias completas, posologia e verificador de interações no app MediHelp

Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.

Explorar de A a Z · Interações medicamentosas

Baixar o app Entrar