Interações medicamentosas
Moxifloxacin + Panobinostat
Gravidade: Contraindicada
Moxifloxacin and Panobinostat: contraindicated interaction.
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Resumo
Panobinostat prolongs the QT interval and its labeling advises against use with other QT-prolonging drugs. Adding moxifloxacin increases the risk of torsades de pointes.
O que esta interação significa em palavras simples
Moxifloxacin and Panobinostat are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Moxifloxacin belongs to Anti Bacterial; Panobinostat belongs to Oncology.
Por que acontece
Additive pharmacodynamic QT prolongation.
O que fazer
Do not combine; select an antibiotic without QT effects. If antibiotic therapy is essential, consider withholding panobinostat and monitor ECG and electrolytes.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicada
- Arsenic trioxide + Moxifloxacin Contraindicada
- Disopyramide + Moxifloxacin Contraindicada
- Dofetilide + Moxifloxacin Contraindicada
- Dronedarone + Moxifloxacin Contraindicada
- Droperidol + Moxifloxacin Contraindicada
Outras interações de Panobinostat
- Amiodarone + Panobinostat Contraindicada
- Anagrelide + Panobinostat Contraindicada
- Chloroquine + Panobinostat Contraindicada
- Chlorpromazine + Panobinostat Contraindicada
- Dronedarone + Panobinostat Contraindicada
- Haloperidol + Panobinostat Contraindicada
Perguntas frequentes
Can I take Moxifloxacin with Panobinostat?
MediHelp rates the interaction as contraindicated. Moxifloxacin and Panobinostat are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Panobinostat prolongs the QT interval and its labeling advises against use with other QT-prolonging drugs. Adding moxifloxacin increases the risk of torsades de pointes.
How serious is the interaction between Moxifloxacin and Panobinostat?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; select an antibiotic without QT effects. If antibiotic therapy is essential, consider withholding panobinostat and monitor ECG and electrolytes.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
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