Interações medicamentosas
Anti-thymocyte + Etrasimod
Gravidade: Grave
Anti-thymocyte and Etrasimod: major interaction.
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Resumo
Etrasimod reduces circulating lymphocytes, and anti-thymocyte globulin profoundly depletes T cells. Used together they may cause additive immunosuppression and a higher risk of serious infection. Combined use has not been studied.
O que esta interação significa em palavras simples
Anti-thymocyte and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anti-thymocyte belongs to Miscellaneous; Etrasimod belongs to Gastrointestinal Tract.
Por que acontece
Additive pharmacodynamic immunosuppression through lymphocyte sequestration (etrasimod) and T-cell depletion (anti-thymocyte globulin).
O que fazer
Avoid combining the two where possible, and allow a sufficient interval after anti-thymocyte globulin before starting etrasimod. If given together, monitor closely for infection and check lymphocyte counts.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Anti-thymocyte
- Anti-thymocyte + Bcg vaccine live Contraindicada
- Anti-thymocyte + Influenza virus vaccine quadrivalent intranasal Contraindicada
- Anti-thymocyte + Measles mumps and rubella vaccine live Contraindicada
- Anti-thymocyte + Measles mumps rubella and varicella vaccine live Contraindicada
- Anti-thymocyte + Measles vaccine Contraindicada
- Anti-thymocyte + Rotavirus oral vaccine live Contraindicada
Outras interações de Etrasimod
- Abatacept + Etrasimod Grave
- Amiodarone + Etrasimod Grave
- Anagrelide + Etrasimod Grave
- Anakinra + Etrasimod Grave
- Asenapine + Etrasimod Grave
- Baricitinib + Etrasimod Grave
Perguntas frequentes
Can I take Anti-thymocyte with Etrasimod?
MediHelp rates the interaction as major. Anti-thymocyte and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Etrasimod reduces circulating lymphocytes, and anti-thymocyte globulin profoundly depletes T cells. Used together they may cause additive immunosuppression and a higher risk of serious infection. Combined use has not been studied.
How serious is the interaction between Anti-thymocyte and Etrasimod?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining the two where possible, and allow a sufficient interval after anti-thymocyte globulin before starting etrasimod. If given together, monitor closely for infection and check lymphocyte counts.
What other medicines interact with Anti-thymocyte?
MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Anti-thymocyte page.
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