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Interações medicamentosas

Anti-thymocyte + Measles mumps rubella and varicella vaccine live

Gravidade: Contraindicada

Anti-thymocyte and Measles mumps rubella and varicella vaccine live: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

This live combination vaccine can cause serious disseminated infection with vaccine viruses in patients immunosuppressed by anti-thymocyte globulin. Vaccine response is also impaired.

O que esta interação significa em palavras simples

Anti-thymocyte and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Nível de evidência: High

Por que acontece

T-cell depletion permits uncontrolled replication of live attenuated viruses.

O que fazer

Do not administer during or after anti-thymocyte globulin until immune reconstitution is confirmed. Vaccinate at least 4 weeks before therapy if feasible.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Anti-thymocyte with Measles mumps rubella and varicella vaccine live?

MediHelp rates the interaction as contraindicated. Anti-thymocyte and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live combination vaccine can cause serious disseminated infection with vaccine viruses in patients immunosuppressed by anti-thymocyte globulin. Vaccine response is also impaired.

How serious is the interaction between Anti-thymocyte and Measles mumps rubella and varicella vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer during or after anti-thymocyte globulin until immune reconstitution is confirmed. Vaccinate at least 4 weeks before therapy if feasible.

What other medicines interact with Anti-thymocyte?

MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Anti-thymocyte page.

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