Interações medicamentosas
Atazanavir + Dronabinol
Gravidade: Moderada
Atazanavir and Dronabinol: moderate interaction.
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Resumo
Atazanavir inhibits CYP3A4 and may raise dronabinol concentrations. This can increase psychoactive and cardiovascular effects such as tachycardia, dizziness, anxiety and sedation.
O que esta interação significa em palavras simples
Atazanavir and Dronabinol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atazanavir belongs to Anti Virals; Dronabinol belongs to Central Nervous System.
Por que acontece
Inhibition of CYP3A4-mediated dronabinol metabolism.
O que fazer
Monitor for excessive CNS effects, tachycardia and hypotension, and lower the dronabinol dose if these occur.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Dronabinol
- Cefotetan + Dronabinol Contraindicada
- Disulfiram + Dronabinol Contraindicada
- Dronabinol + Midazolam intranasal Grave
- Dronabinol + Zuranolone Grave
- Amobarbital + Dronabinol Moderada
- Apalutamide + Dronabinol Moderada
Outras interações de Atazanavir
- Alfuzosin + Atazanavir Contraindicada
- Atazanavir + Avanafil Contraindicada
- Atazanavir + Dronedarone Contraindicada
- Atazanavir + Eletriptan Contraindicada
- Atazanavir + Eplerenone Contraindicada
- Atazanavir + Ergotamine Contraindicada
Perguntas frequentes
Can I take Atazanavir with Dronabinol?
MediHelp rates the interaction as moderate. Atazanavir and Dronabinol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atazanavir inhibits CYP3A4 and may raise dronabinol concentrations. This can increase psychoactive and cardiovascular effects such as tachycardia, dizziness, anxiety and sedation.
How serious is the interaction between Atazanavir and Dronabinol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive CNS effects, tachycardia and hypotension, and lower the dronabinol dose if these occur.
What other medicines interact with Dronabinol?
MediHelp also lists interactions of Dronabinol with, for example, Cefotetan, Disulfiram, Midazolam intranasal. The full list is on the Dronabinol page.
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