Interações medicamentosas
Atenolol + Bismuth subsalicylate
Gravidade: Moderada
Atenolol and Bismuth subsalicylate: moderate interaction.
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Resumo
Bismuth subsalicylate releases salicylate, which may inhibit renal prostaglandin synthesis, causing sodium and water retention and blunting the antihypertensive effect of beta-blockers. The effect is chiefly seen with regular high-dose salicylate use and is generally modest with short courses.
O que esta interação significa em palavras simples
Atenolol and Bismuth subsalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol belongs to Cardiovascular; Bismuth subsalicylate belongs to Gastrointestinal Tract.
Por que acontece
Salicylate inhibits prostaglandin synthesis, causing sodium and fluid retention that opposes the antihypertensive effect.
O que fazer
Limit bismuth subsalicylate to short courses and monitor blood pressure if used repeatedly. Use an alternative antidiarrheal or antacid for prolonged treatment.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Bismuth subsalicylate
- Bismuth subsalicylate + Dichlorphenamide Grave
- Bismuth subsalicylate + Warfarin Grave
- Acetylsalicylic acid + Bismuth subsalicylate Moderada
- Amlodipine-benazepril + Bismuth subsalicylate Moderada
- Aspirin / citric acid / sodium bicarbonate + Bismuth subsalicylate Moderada
- Aspirin rectal + Bismuth subsalicylate Moderada
Outras interações de Atenolol
- Amifostine + Atenolol Grave
- Amiodarone + Atenolol Grave
- Atenolol + Atenolol-chlorthalidone Grave
- Atenolol + Betaxolol Grave
- Atenolol + Bisoprolol Grave
- Atenolol + Carvedilol Grave
Perguntas frequentes
Can I take Atenolol with Bismuth subsalicylate?
MediHelp rates the interaction as moderate. Atenolol and Bismuth subsalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bismuth subsalicylate releases salicylate, which may inhibit renal prostaglandin synthesis, causing sodium and water retention and blunting the antihypertensive effect of beta-blockers. The effect is chiefly seen with regular high-dose salicylate use and is generally modest with short courses.
How serious is the interaction between Atenolol and Bismuth subsalicylate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Limit bismuth subsalicylate to short courses and monitor blood pressure if used repeatedly. Use an alternative antidiarrheal or antacid for prolonged treatment.
What other medicines interact with Bismuth subsalicylate?
MediHelp also lists interactions of Bismuth subsalicylate with, for example, Dichlorphenamide, Warfarin, Acetylsalicylic acid. The full list is on the Bismuth subsalicylate page.
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