Interações medicamentosas
Atomoxetine + Isocarboxazid
Gravidade: Contraindicada
Atomoxetine and Isocarboxazid: contraindicated interaction.
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Resumo
Isocarboxazid inhibits monoamine oxidase, and atomoxetine raises synaptic noradrenaline. The combination has led to hypertensive reactions, hyperthermia, rigidity and altered consciousness.
O que esta interação significa em palavras simples
Atomoxetine and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Atomoxetine belongs to Central Nervous System; Isocarboxazid belongs to Central Nervous System.
Por que acontece
MAO inhibition plus noradrenaline reuptake inhibition causes excessive adrenergic stimulation
O que fazer
Do not use together; wait at least 14 days after stopping a MAOI before starting atomoxetine, and 2 days the other way round.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Atomoxetine
- Atomoxetine + Linezolid Contraindicada
- Atomoxetine + Phenelzine Contraindicada
- Atomoxetine + Procarbazine Contraindicada
- Atomoxetine + Rasagiline Contraindicada
- Atomoxetine + Selegiline Contraindicada
- Atomoxetine + Selegiline transdermal Contraindicada
Outras interações de Isocarboxazid
- 5-HTP + Isocarboxazid Contraindicada
- Amitriptyline + Isocarboxazid Contraindicada
- Amobarbital + Isocarboxazid Contraindicada
- Amoxapine + Isocarboxazid Contraindicada
- Apraclonidine + Isocarboxazid Contraindicada
- Benzphetamine + Isocarboxazid Contraindicada
Perguntas frequentes
Can I take Atomoxetine with Isocarboxazid?
MediHelp rates the interaction as contraindicated. Atomoxetine and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Isocarboxazid inhibits monoamine oxidase, and atomoxetine raises synaptic noradrenaline. The combination has led to hypertensive reactions, hyperthermia, rigidity and altered consciousness.
How serious is the interaction between Atomoxetine and Isocarboxazid?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; wait at least 14 days after stopping a MAOI before starting atomoxetine, and 2 days the other way round.
What other medicines interact with Atomoxetine?
MediHelp also lists interactions of Atomoxetine with, for example, Linezolid, Phenelzine, Procarbazine. The full list is on the Atomoxetine page.
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