Interações medicamentosas
Atropine + Bethanechol
Gravidade: Moderada
Atropine and Bethanechol: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Atropine is a competitive muscarinic antagonist and directly opposes the muscarinic agonist effects of bethanechol on the bladder, gut and other organs. Bethanechol may therefore lose its efficacy, and atropine can be used to reverse bethanechol toxicity.
O que esta interação significa em palavras simples
Atropine and Bethanechol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atropine belongs to Miscellaneous; Bethanechol belongs to Gastrointestinal Tract.
Por que acontece
Pharmacodynamic antagonism at muscarinic receptors.
O que fazer
Avoid routine co-administration because therapeutic effect is lost; if bethanechol overdose or cholinergic toxicity occurs, atropine is the appropriate antidote.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Bethanechol
- Bethanechol + Darifenacin Grave
- Bethanechol + Fesoterodine Grave
- Bethanechol + Oxybutynin Grave
- Bethanechol + Physostigmine Grave
- Amifampridine + Bethanechol Moderada
- Amitriptyline + Bethanechol Moderada
Outras interações de Atropine
- Atropine + Eluxadoline Grave
- Atropine + Henbane Grave
- Atropine + Pramlintide Grave
- Abobotulinumtoxina + Atropine Moderada
- Aclidinium + Atropine Moderada
- Amantadine + Atropine Moderada
Perguntas frequentes
Can I take Atropine with Bethanechol?
MediHelp rates the interaction as moderate. Atropine and Bethanechol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atropine is a competitive muscarinic antagonist and directly opposes the muscarinic agonist effects of bethanechol on the bladder, gut and other organs. Bethanechol may therefore lose its efficacy, and atropine can be used to reverse bethanechol toxicity.
How serious is the interaction between Atropine and Bethanechol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine co-administration because therapeutic effect is lost; if bethanechol overdose or cholinergic toxicity occurs, atropine is the appropriate antidote.
What other medicines interact with Bethanechol?
MediHelp also lists interactions of Bethanechol with, for example, Darifenacin, Fesoterodine, Oxybutynin. The full list is on the Bethanechol page.
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