Pular para o conteúdo

Interações medicamentosas

Bethanechol + Fesoterodine

Gravidade: Grave

Bethanechol and Fesoterodine: major interaction.

Última atualização

Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Fesoterodine is converted to an active antimuscarinic metabolite that opposes bethanechol's bladder-stimulating effect. The drugs have opposing actions and negate each other.

O que esta interação significa em palavras simples

Bethanechol and Fesoterodine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Bethanechol belongs to Gastrointestinal Tract; Fesoterodine belongs to Genitourinary.

Nível de evidência: Moderate

Por que acontece

Competitive muscarinic antagonism by the active metabolite of fesoterodine against bethanechol.

O que fazer

Avoid combining; reassess the underlying bladder dysfunction and select one therapy.

O que perguntar ao farmacêutico

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Para assinantes do Pro+

Desbloqueie a página completa

Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Bethanechol e Fesoterodine, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Experimente o Pro+ grátis por 14 dias na web. Sem cartão.

Perguntas frequentes

Can I take Bethanechol with Fesoterodine?

MediHelp rates the interaction as major. Bethanechol and Fesoterodine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Fesoterodine is converted to an active antimuscarinic metabolite that opposes bethanechol's bladder-stimulating effect. The drugs have opposing actions and negate each other.

How serious is the interaction between Bethanechol and Fesoterodine?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining; reassess the underlying bladder dysfunction and select one therapy.

What other medicines interact with Bethanechol?

MediHelp also lists interactions of Bethanechol with, for example, Darifenacin, Oxybutynin, Physostigmine. The full list is on the Bethanechol page.

Monografias completas, posologia e verificador de interações no app MediHelp

Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.

Explorar de A a Z · Interações medicamentosas

Baixar o app Entrar