Interações medicamentosas
Bacitracin + Colistin
Gravidade: Grave
Bacitracin and Colistin: major interaction.
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Resumo
Systemic bacitracin is markedly nephrotoxic, and combining it with colistin compounds the risk of kidney injury. Neurotoxicity and neuromuscular effects may also be additive.
O que esta interação significa em palavras simples
Bacitracin and Colistin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bacitracin belongs to Miscellaneous; Colistin belongs to Anti Bacterial.
Por que acontece
Additive nephrotoxicity through renal tubular injury.
O que fazer
Avoid systemic combination; if unavoidable, monitor renal function daily and adjust doses to creatinine clearance.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Colistin
- Colistin + Polymyxin b Contraindicada
- Amikacin + Colistin Grave
- Amphotericin b deoxycholate + Colistin Grave
- Amphotericin b + Colistin Grave
- Atracurium + Colistin Grave
- Capreomycin + Colistin Grave
Outras interações de Bacitracin
- Bacitracin + Cidofovir Contraindicada
- Adefovir + Bacitracin Grave
- Aldesleukin + Bacitracin Grave
- Amikacin + Bacitracin Grave
- Bacitracin + Carboplatin Grave
- Bacitracin + Cisplatin Grave
Perguntas frequentes
Can I take Bacitracin with Colistin?
MediHelp rates the interaction as major. Bacitracin and Colistin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Systemic bacitracin is markedly nephrotoxic, and combining it with colistin compounds the risk of kidney injury. Neurotoxicity and neuromuscular effects may also be additive.
How serious is the interaction between Bacitracin and Colistin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic combination; if unavoidable, monitor renal function daily and adjust doses to creatinine clearance.
What other medicines interact with Colistin?
MediHelp also lists interactions of Colistin with, for example, Polymyxin b, Amikacin, Amphotericin b deoxycholate. The full list is on the Colistin page.
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