Interações medicamentosas
Baloxavir marboxil + Calcium carbonate
Gravidade: Moderada
Baloxavir marboxil and Calcium carbonate: moderate interaction.
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Resumo
Baloxavir can chelate polyvalent cations such as calcium in the gut, which may reduce its absorption and lower antiviral exposure. Reduced exposure could compromise treatment of influenza.
O que esta interação significa em palavras simples
Baloxavir marboxil and Calcium carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Baloxavir marboxil belongs to Anti Virals; Calcium carbonate belongs to Gastrointestinal Tract.
Por que acontece
Chelation of baloxavir by calcium in the gastrointestinal tract reduces its oral absorption.
O que fazer
Avoid taking baloxavir together with calcium-containing antacids or supplements; if calcium is needed, give it at a separate time from baloxavir. Labeling advises avoiding co-administration with polyvalent cation products.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Calcium carbonate
Outras interações de Baloxavir marboxil
- Aluminum hydroxide + Baloxavir marboxil Moderada
- Baloxavir marboxil + Calcium Moderada
- Baloxavir marboxil + Carbonyl iron Moderada
- Baloxavir marboxil + Ferrous fumarate Moderada
- Baloxavir marboxil + Ferrous gluconate Moderada
- Baloxavir marboxil + Ferrous sulfate Moderada
Perguntas frequentes
Can I take Baloxavir marboxil with Calcium carbonate?
MediHelp rates the interaction as moderate. Baloxavir marboxil and Calcium carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Baloxavir can chelate polyvalent cations such as calcium in the gut, which may reduce its absorption and lower antiviral exposure. Reduced exposure could compromise treatment of influenza.
How serious is the interaction between Baloxavir marboxil and Calcium carbonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid taking baloxavir together with calcium-containing antacids or supplements; if calcium is needed, give it at a separate time from baloxavir. Labeling advises avoiding co-administration with polyvalent cation products.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
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