Interações medicamentosas
Balsalazide + Celecoxib
Gravidade: Moderada
Balsalazide and Celecoxib: moderate interaction.
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Resumo
Balsalazide releases mesalamine in the colon, and celecoxib is an NSAID with renal effects. Concurrent use may add to the risk of renal impairment, especially with dehydration or pre-existing kidney disease. NSAIDs may also aggravate inflammatory bowel disease in some patients.
O que esta interação significa em palavras simples
Balsalazide and Celecoxib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Balsalazide belongs to Gastrointestinal Tract; Celecoxib belongs to Musculoskeletal.
Por que acontece
Additive nephrotoxic potential from NSAID-mediated prostaglandin inhibition and rare mesalamine-related interstitial nephritis.
O que fazer
Monitor renal function periodically and watch for worsening bowel symptoms. Avoid long-term NSAID use where an alternative analgesic is suitable.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Balsalazide
Outras interações de Celecoxib
- Celecoxib + Ketorolac Contraindicada
- Celecoxib + Ketorolac intranasal Contraindicada
- Aceclofenac + Celecoxib Grave
- Acemetacin + Celecoxib Grave
- Amiloride + Celecoxib Grave
- Apixaban + Celecoxib Grave
Perguntas frequentes
Can I take Balsalazide with Celecoxib?
MediHelp rates the interaction as moderate. Balsalazide and Celecoxib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Balsalazide releases mesalamine in the colon, and celecoxib is an NSAID with renal effects. Concurrent use may add to the risk of renal impairment, especially with dehydration or pre-existing kidney disease. NSAIDs may also aggravate inflammatory bowel disease in some patients.
How serious is the interaction between Balsalazide and Celecoxib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function periodically and watch for worsening bowel symptoms. Avoid long-term NSAID use where an alternative analgesic is suitable.
What other medicines interact with Balsalazide?
MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Balsalazide page.
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