Interações medicamentosas
Baricitinib + Deferiprone
Gravidade: Grave
Baricitinib and Deferiprone: major interaction.
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Resumo
Deferiprone can cause agranulocytosis and neutropenia, and baricitinib also suppresses immune function and can lower blood counts. Together they increase the risk of serious infection.
O que esta interação significa em palavras simples
Baricitinib and Deferiprone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Baricitinib belongs to Musculoskeletal; Deferiprone belongs to Miscellaneous.
Por que acontece
Additive myelosuppressive and immunosuppressive effects.
O que fazer
Avoid the combination where possible. If both are needed, monitor absolute neutrophil counts frequently and watch for infection.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Baricitinib
- Adenovirus types 4 and 7 live + Baricitinib Contraindicada
- Baricitinib + Bcg vaccine live Contraindicada
- Baricitinib + Tofacitinib Contraindicada
- Baricitinib + Upadacitinib Contraindicada
- Abatacept + Baricitinib Grave
- Adalimumab + Baricitinib Grave
Outras interações de Deferiprone
- Clozapine + Deferiprone Contraindicada
- Abemaciclib + Deferiprone Grave
- Acalabrutinib + Deferiprone Grave
- Ado-trastuzumab emtansine + Deferiprone Grave
- Ado-trastuzumab + Deferiprone Grave
- Aldesleukin + Deferiprone Grave
Perguntas frequentes
Can I take Baricitinib with Deferiprone?
MediHelp rates the interaction as major. Baricitinib and Deferiprone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Deferiprone can cause agranulocytosis and neutropenia, and baricitinib also suppresses immune function and can lower blood counts. Together they increase the risk of serious infection.
How serious is the interaction between Baricitinib and Deferiprone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible. If both are needed, monitor absolute neutrophil counts frequently and watch for infection.
What other medicines interact with Baricitinib?
MediHelp also lists interactions of Baricitinib with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Tofacitinib. The full list is on the Baricitinib page.
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