Interações medicamentosas
Baricitinib + Upadacitinib
Gravidade: Contraindicada
Baricitinib and Upadacitinib: contraindicated interaction.
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Resumo
Baricitinib and upadacitinib are both JAK inhibitors, so using them together duplicates therapy without proven benefit. Exposure to JAK-related adverse effects such as serious infection, thrombosis, cytopenias and lipid rise is doubled.
O que esta interação significa em palavras simples
Baricitinib and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Baricitinib belongs to Musculoskeletal; Upadacitinib belongs to Musculoskeletal.
Por que acontece
Therapeutic duplication of JAK inhibition
O que fazer
Do not combine; if switching between JAK inhibitors, stop the first agent before starting the second.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Baricitinib
- Adenovirus types 4 and 7 live + Baricitinib Contraindicada
- Baricitinib + Bcg vaccine live Contraindicada
- Baricitinib + Tofacitinib Contraindicada
- Abatacept + Baricitinib Grave
- Adalimumab + Baricitinib Grave
- Ado-trastuzumab + Baricitinib Grave
Outras interações de Upadacitinib
- Abrocitinib + Upadacitinib Contraindicada
- Adenovirus types 4 and 7 live + Upadacitinib Contraindicada
- Bcg vaccine live + Upadacitinib Contraindicada
- Cyclosporine + Upadacitinib Contraindicada
- Dengue vaccine + Upadacitinib Contraindicada
- Influenza virus vaccine quadrivalent intranasal + Upadacitinib Contraindicada
Perguntas frequentes
Can I take Baricitinib with Upadacitinib?
MediHelp rates the interaction as contraindicated. Baricitinib and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Baricitinib and upadacitinib are both JAK inhibitors, so using them together duplicates therapy without proven benefit. Exposure to JAK-related adverse effects such as serious infection, thrombosis, cytopenias and lipid rise is doubled.
How serious is the interaction between Baricitinib and Upadacitinib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; if switching between JAK inhibitors, stop the first agent before starting the second.
What other medicines interact with Baricitinib?
MediHelp also lists interactions of Baricitinib with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Tofacitinib. The full list is on the Baricitinib page.
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