Interações medicamentosas
Bcg intravesical live + Certolizumab pegol
Gravidade: Contraindicada
Bcg intravesical live and Certolizumab pegol: contraindicated interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Intravesical BCG is live Mycobacterium bovis. In patients on a TNF inhibitor, impaired granulomatous immunity may permit systemic BCG infection (BCGosis), and the antitumor response may be reduced.
O que esta interação significa em palavras simples
Bcg intravesical live and Certolizumab pegol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
TNF is essential for granuloma formation and mycobacterial containment, so its inhibition allows BCG dissemination.
O que fazer
Avoid intravesical BCG during certolizumab therapy and consider alternative bladder cancer treatment. If BCG is essential, discuss pausing certolizumab with the treating specialists.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Certolizumab pegol
- Adenovirus types 4 and 7 live + Certolizumab pegol Contraindicada
- Bcg vaccine live + Certolizumab pegol Contraindicada
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal Contraindicada
- Certolizumab pegol + Measles mumps and rubella vaccine Contraindicada
- Certolizumab pegol + Measles mumps and rubella vaccine live Contraindicada
- Certolizumab pegol + Measles mumps rubella and varicella vaccine live Contraindicada
Perguntas frequentes
Can I take Bcg intravesical live with Certolizumab pegol?
MediHelp rates the interaction as contraindicated. Bcg intravesical live and Certolizumab pegol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Intravesical BCG is live Mycobacterium bovis. In patients on a TNF inhibitor, impaired granulomatous immunity may permit systemic BCG infection (BCGosis), and the antitumor response may be reduced.
How serious is the interaction between Bcg intravesical live and Certolizumab pegol?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid intravesical BCG during certolizumab therapy and consider alternative bladder cancer treatment. If BCG is essential, discuss pausing certolizumab with the treating specialists.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Certolizumab pegol page.
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