Interações medicamentosas
Bcg vaccine live + Hydrocortisone
Gravidade: Grave
Bcg vaccine live and Hydrocortisone: major interaction.
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Resumo
Live BCG given to patients on immunosuppressive corticosteroid doses may cause disseminated BCG infection. Corticosteroids also reduce the immune response to the vaccine.
O que esta interação significa em palavras simples
Bcg vaccine live and Hydrocortisone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Por que acontece
Corticosteroid immunosuppression permits uncontrolled replication of live attenuated organisms.
O que fazer
Avoid live BCG in patients on immunosuppressive doses; defer vaccination until steroids are stopped or reduced to low doses, as per product labeling.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Hydrocortisone
- Hydrocortisone + Mifepristone Contraindicada
- Hydrocortisone + Poliovirus vaccine live oral trivalent Contraindicada
- Hydrocortisone + Smallpox vaccine live Contraindicada
- Adenovirus types 4 and 7 live + Hydrocortisone Grave
- Aldesleukin + Hydrocortisone Grave
- Aspirin + Hydrocortisone Grave
Perguntas frequentes
Can I take Bcg vaccine live with Hydrocortisone?
MediHelp rates the interaction as major. Bcg vaccine live and Hydrocortisone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Live BCG given to patients on immunosuppressive corticosteroid doses may cause disseminated BCG infection. Corticosteroids also reduce the immune response to the vaccine.
How serious is the interaction between Bcg vaccine live and Hydrocortisone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live BCG in patients on immunosuppressive doses; defer vaccination until steroids are stopped or reduced to low doses, as per product labeling.
What other medicines interact with Hydrocortisone?
MediHelp also lists interactions of Hydrocortisone with, for example, Mifepristone, Poliovirus vaccine live oral trivalent, Smallpox vaccine live. The full list is on the Hydrocortisone page.
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