Interações medicamentosas
Hydrocortisone + Smallpox vaccine live
Gravidade: Contraindicada
Hydrocortisone and Smallpox vaccine live: contraindicated interaction.
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Resumo
Live vaccinia vaccine can cause progressive vaccinia and other severe complications in immunocompromised patients. Corticosteroid immunosuppression increases this risk and may reduce vaccine take.
O que esta interação significa em palavras simples
Hydrocortisone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Corticosteroid-induced immunosuppression allows uncontrolled replication of live vaccinia virus.
O que fazer
Avoid in patients on immunosuppressive corticosteroids unless the benefit clearly outweighs risk, such as in post-exposure outbreak settings, and seek specialist advice. Use a non-replicating vaccine if available.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Hydrocortisone
- Hydrocortisone + Mifepristone Contraindicada
- Hydrocortisone + Poliovirus vaccine live oral trivalent Contraindicada
- Adenovirus types 4 and 7 live + Hydrocortisone Grave
- Aldesleukin + Hydrocortisone Grave
- Aspirin + Hydrocortisone Grave
- Bcg vaccine live + Hydrocortisone Grave
Perguntas frequentes
Can I take Hydrocortisone with Smallpox vaccine live?
MediHelp rates the interaction as contraindicated. Hydrocortisone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live vaccinia vaccine can cause progressive vaccinia and other severe complications in immunocompromised patients. Corticosteroid immunosuppression increases this risk and may reduce vaccine take.
How serious is the interaction between Hydrocortisone and Smallpox vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients on immunosuppressive corticosteroids unless the benefit clearly outweighs risk, such as in post-exposure outbreak settings, and seek specialist advice. Use a non-replicating vaccine if available.
What other medicines interact with Hydrocortisone?
MediHelp also lists interactions of Hydrocortisone with, for example, Mifepristone, Poliovirus vaccine live oral trivalent, Adenovirus types 4 and 7 live. The full list is on the Hydrocortisone page.
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