Interações medicamentosas
Hydrocortisone + Poliovirus vaccine live oral trivalent
Gravidade: Contraindicada
Hydrocortisone and Poliovirus vaccine live oral trivalent: contraindicated interaction.
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Resumo
Oral polio vaccine is live attenuated and in immunosuppressed patients can cause vaccine-associated paralytic poliomyelitis. Immunosuppressive doses of hydrocortisone also reduce immune response.
O que esta interação significa em palavras simples
Hydrocortisone and Poliovirus vaccine live oral trivalent are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Corticosteroid-induced immunosuppression permits prolonged replication of live attenuated poliovirus and reduces immunogenicity.
O que fazer
Do not use live oral polio vaccine in patients on immunosuppressive corticosteroids; use inactivated polio vaccine instead. Household contacts should also preferably receive inactivated vaccine.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Hydrocortisone
- Hydrocortisone + Mifepristone Contraindicada
- Hydrocortisone + Smallpox vaccine live Contraindicada
- Adenovirus types 4 and 7 live + Hydrocortisone Grave
- Aldesleukin + Hydrocortisone Grave
- Aspirin + Hydrocortisone Grave
- Bcg vaccine live + Hydrocortisone Grave
Perguntas frequentes
Can I take Hydrocortisone with Poliovirus vaccine live oral trivalent?
MediHelp rates the interaction as contraindicated. Hydrocortisone and Poliovirus vaccine live oral trivalent are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Oral polio vaccine is live attenuated and in immunosuppressed patients can cause vaccine-associated paralytic poliomyelitis. Immunosuppressive doses of hydrocortisone also reduce immune response.
How serious is the interaction between Hydrocortisone and Poliovirus vaccine live oral trivalent?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use live oral polio vaccine in patients on immunosuppressive corticosteroids; use inactivated polio vaccine instead. Household contacts should also preferably receive inactivated vaccine.
What other medicines interact with Hydrocortisone?
MediHelp also lists interactions of Hydrocortisone with, for example, Mifepristone, Smallpox vaccine live, Adenovirus types 4 and 7 live. The full list is on the Hydrocortisone page.
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