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Interações medicamentosas

Bcg vaccine live + Oxaliplatin

Gravidade: Contraindicada

Bcg vaccine live and Oxaliplatin: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

In patients immunosuppressed by oxaliplatin, live BCG may cause disseminated BCG infection and the vaccine may be less effective.

O que esta interação significa em palavras simples

Bcg vaccine live and Oxaliplatin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Nível de evidência: High

Por que acontece

Cytotoxic immunosuppression impairs control of live vaccine bacteria and reduces the immune response.

O que fazer

Do not give BCG during oxaliplatin therapy; defer until immune recovery, generally at least 3 months after treatment ends.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

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Perguntas frequentes

Can I take Bcg vaccine live with Oxaliplatin?

MediHelp rates the interaction as contraindicated. Bcg vaccine live and Oxaliplatin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. In patients immunosuppressed by oxaliplatin, live BCG may cause disseminated BCG infection and the vaccine may be less effective.

How serious is the interaction between Bcg vaccine live and Oxaliplatin?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG during oxaliplatin therapy; defer until immune recovery, generally at least 3 months after treatment ends.

What other medicines interact with Oxaliplatin?

MediHelp also lists interactions of Oxaliplatin with, for example, Adenovirus types 4 and 7 live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Oxaliplatin page.

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