Interações medicamentosas
Bcg vaccine live + Piperacillin-tazobactam
Gravidade: Moderada
Bcg vaccine live and Piperacillin-tazobactam: moderate interaction.
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Resumo
Live BCG contains viable bacteria, and antibiotics active against them can reduce vaccine take. Piperacillin-tazobactam has limited activity against BCG, but concurrent antibiotics are generally avoided around live bacterial vaccination.
O que esta interação significa em palavras simples
Bcg vaccine live and Piperacillin-tazobactam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Antibacterial activity may reduce replication of the live vaccine organism, lessening the immune response.
O que fazer
Defer BCG vaccination until the antibiotic course is complete, unless vaccination is urgent.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Piperacillin-tazobactam
Perguntas frequentes
Can I take Bcg vaccine live with Piperacillin-tazobactam?
MediHelp rates the interaction as moderate. Bcg vaccine live and Piperacillin-tazobactam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Live BCG contains viable bacteria, and antibiotics active against them can reduce vaccine take. Piperacillin-tazobactam has limited activity against BCG, but concurrent antibiotics are generally avoided around live bacterial vaccination.
How serious is the interaction between Bcg vaccine live and Piperacillin-tazobactam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Defer BCG vaccination until the antibiotic course is complete, unless vaccination is urgent.
What other medicines interact with Piperacillin-tazobactam?
MediHelp also lists interactions of Piperacillin-tazobactam with, for example, Vancomycin, Amikacin, Antithrombin alfa. The full list is on the Piperacillin-tazobactam page.
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