Interações medicamentosas
Benazepril + Potassium chloride
Gravidade: Grave
Benazepril and Potassium chloride: major interaction.
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Resumo
Benazepril reduces renal potassium loss, and added potassium chloride can lead to clinically significant hyperkalemia with arrhythmia risk. Patients with kidney disease or diabetes are at the highest risk.
O que esta interação significa em palavras simples
Benazepril and Potassium chloride can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Benazepril belongs to Cardiovascular; Potassium chloride belongs to Gastrointestinal Tract.
Por que acontece
ACE inhibition suppresses aldosterone and decreases potassium excretion, compounding the exogenous potassium load.
O que fazer
Use potassium chloride only when clearly indicated, with serum potassium and creatinine checks soon after starting and regularly thereafter. Lower or stop the supplement if potassium approaches the upper normal range.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Benazepril
- Aliskiren + Benazepril Contraindicada
- Benazepril + Sacubitril / valsartan Contraindicada
- Benazepril + Sacubitril-valsartan Contraindicada
- Amifostine + Benazepril Grave
- Amiloride + Benazepril Grave
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Grave
Outras interações de Potassium chloride
Perguntas frequentes
Can I take Benazepril with Potassium chloride?
MediHelp rates the interaction as major. Benazepril and Potassium chloride can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Benazepril reduces renal potassium loss, and added potassium chloride can lead to clinically significant hyperkalemia with arrhythmia risk. Patients with kidney disease or diabetes are at the highest risk.
How serious is the interaction between Benazepril and Potassium chloride?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use potassium chloride only when clearly indicated, with serum potassium and creatinine checks soon after starting and regularly thereafter. Lower or stop the supplement if potassium approaches the upper normal range.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
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