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Interações medicamentosas

Benzphetamine + Phenelzine

Gravidade: Contraindicada

Benzphetamine and Phenelzine: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

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Resumo

Benzphetamine is a sympathomimetic anorectic, and with MAO inhibitors it can trigger hypertensive crisis. Headache, severe hypertension, and intracranial hemorrhage are possible.

O que esta interação significa em palavras simples

Benzphetamine and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Nível de evidência: High

Por que acontece

MAO inhibition allows accumulation of norepinephrine, which is released by benzphetamine, producing excessive pressor response.

O que fazer

Do not use together or within 14 days of stopping phenelzine. Use a non-sympathomimetic weight management approach.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Benzphetamine with Phenelzine?

MediHelp rates the interaction as contraindicated. Benzphetamine and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Benzphetamine is a sympathomimetic anorectic, and with MAO inhibitors it can trigger hypertensive crisis. Headache, severe hypertension, and intracranial hemorrhage are possible.

How serious is the interaction between Benzphetamine and Phenelzine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together or within 14 days of stopping phenelzine. Use a non-sympathomimetic weight management approach.

What other medicines interact with Phenelzine?

MediHelp also lists interactions of Phenelzine with, for example, 5-HTP, Amitriptyline, Amoxapine. The full list is on the Phenelzine page.

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