Interações medicamentosas
Betaxolol + Clonidine
Gravidade: Grave
Betaxolol and Clonidine: major interaction.
Última atualização
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Resumo
Both lower heart rate and blood pressure, so together they can cause marked bradycardia and hypotension. If clonidine is stopped while a beta-blocker continues, rebound hypertension can be exaggerated.
O que esta interação significa em palavras simples
Betaxolol and Clonidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Betaxolol belongs to Cardiovascular; Clonidine belongs to Cardiovascular.
Por que acontece
Additive effects of central sympatholysis and beta-blockade; unopposed alpha stimulation during clonidine withdrawal on beta-blockade.
O que fazer
Monitor heart rate and blood pressure. When stopping, withdraw the beta-blocker several days before gradually tapering clonidine.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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- Additional notes
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Outras interações de Betaxolol
- Acebutolol + Betaxolol Grave
- Aldesleukin + Betaxolol Grave
- Amifostine + Betaxolol Grave
- Amiodarone + Betaxolol Grave
- Atenolol-chlorthalidone + Betaxolol Grave
- Atenolol + Betaxolol Grave
Outras interações de Clonidine
- Acebutolol + Clonidine Grave
- Amifostine + Clonidine Grave
- Amiodarone + Clonidine Grave
- Amoxapine + Clonidine Grave
- Atenolol-chlorthalidone + Clonidine Grave
- Atenolol + Clonidine Grave
Perguntas frequentes
Can I take Betaxolol with Clonidine?
MediHelp rates the interaction as major. Betaxolol and Clonidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both lower heart rate and blood pressure, so together they can cause marked bradycardia and hypotension. If clonidine is stopped while a beta-blocker continues, rebound hypertension can be exaggerated.
How serious is the interaction between Betaxolol and Clonidine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure. When stopping, withdraw the beta-blocker several days before gradually tapering clonidine.
What other medicines interact with Betaxolol?
MediHelp also lists interactions of Betaxolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Betaxolol page.
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