Interações medicamentosas
Brexpiprazole + Dexbrompheniramine
Gravidade: Moderada
Brexpiprazole and Dexbrompheniramine: moderate interaction.
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Resumo
Both drugs cause sedation, so taking them together can deepen drowsiness and impair alertness, psychomotor performance and driving ability. The effect is most relevant in older patients and at treatment initiation.
O que esta interação significa em palavras simples
Brexpiprazole and Dexbrompheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brexpiprazole belongs to Central Nervous System; Dexbrompheniramine belongs to Respiratory.
Por que acontece
Additive CNS depression from antihistaminergic and antipsychotic sedative effects.
O que fazer
Warn patients about drowsiness and avoid driving or hazardous tasks until response is known. Prefer a non-sedating antihistamine if one is needed.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Brexpiprazole
Outras interações de Dexbrompheniramine
- Amisulpride + Dexbrompheniramine Moderada
- Asenapine + Dexbrompheniramine Moderada
- Brimonidine + Dexbrompheniramine Moderada
- Brivaracetam + Dexbrompheniramine Moderada
- Cariprazine + Dexbrompheniramine Moderada
- Dexbrompheniramine + Esketamine Moderada
Perguntas frequentes
Can I take Brexpiprazole with Dexbrompheniramine?
MediHelp rates the interaction as moderate. Brexpiprazole and Dexbrompheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs cause sedation, so taking them together can deepen drowsiness and impair alertness, psychomotor performance and driving ability. The effect is most relevant in older patients and at treatment initiation.
How serious is the interaction between Brexpiprazole and Dexbrompheniramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Warn patients about drowsiness and avoid driving or hazardous tasks until response is known. Prefer a non-sedating antihistamine if one is needed.
What other medicines interact with Brexpiprazole?
MediHelp also lists interactions of Brexpiprazole with, for example, Alfentanil, Amisulpride, Apalutamide. The full list is on the Brexpiprazole page.
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