Interações medicamentosas
Bromocriptine + Dihydroergotamine intranasal
Gravidade: Grave
Bromocriptine and Dihydroergotamine intranasal: major interaction.
Última atualização Fontes: US FDA label
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Intranasal dihydroergotamine is absorbed systemically and combined with bromocriptine may add to ergot-related vasoconstriction, causing hypertension, vasospasm or peripheral ischemia. The combination offers little benefit relative to its risk.
O que esta interação significa em palavras simples
Bromocriptine and Dihydroergotamine intranasal can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Por que acontece
Additive pharmacodynamic vasoconstrictive and ergot-related effects at vascular receptors.
O que fazer
Avoid the combination and use a non-ergot migraine therapy if bromocriptine is required. If both are used, monitor blood pressure and for signs of ischemia.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Bromocriptine e Dihydroergotamine intranasal, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 7 dias na web. Sem cartão.
Referências
Outras interações de Bromocriptine
Perguntas frequentes
Can I take Bromocriptine with Dihydroergotamine intranasal?
MediHelp rates the interaction as major. Bromocriptine and Dihydroergotamine intranasal can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Intranasal dihydroergotamine is absorbed systemically and combined with bromocriptine may add to ergot-related vasoconstriction, causing hypertension, vasospasm or peripheral ischemia. The combination offers little benefit relative to its risk.
How serious is the interaction between Bromocriptine and Dihydroergotamine intranasal?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use a non-ergot migraine therapy if bromocriptine is required. If both are used, monitor blood pressure and for signs of ischemia.
What other medicines interact with Bromocriptine?
MediHelp also lists interactions of Bromocriptine with, for example, Amisulpride, Atazanavir, Cobicistat. The full list is on the Bromocriptine page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
