Interações medicamentosas
Bromocriptine + Dihydroergotamine
Gravidade: Grave
Bromocriptine and Dihydroergotamine: major interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Both drugs are ergot derivatives with vasoconstrictive activity, so combined use may add to the risk of ergotism, including hypertension, peripheral ischemia and vasospasm. Dihydroergotamine also has serotonergic and adrenergic effects that add to bromocriptine's vascular effects.
O que esta interação significa em palavras simples
Bromocriptine and Dihydroergotamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bromocriptine belongs to Central Nervous System; Dihydroergotamine belongs to Central Nervous System.
Por que acontece
Additive pharmacodynamic vasoconstrictive and ergot-related effects at vascular receptors.
O que fazer
Avoid concurrent use; choose a non-ergot alternative for migraine or for the dopamine agonist indication. If unavoidable, monitor for ischemic symptoms and blood pressure elevation.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Bromocriptine e Dihydroergotamine, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 7 dias na web. Sem cartão.
Outras interações de Bromocriptine
Outras interações de Dihydroergotamine
- Almotriptan + Dihydroergotamine Contraindicada
- Clarithromycin + Dihydroergotamine Contraindicada
- Dihydroergotamine + Dopamine Contraindicada
- Dihydroergotamine + Dronedarone Contraindicada
- Dihydroergotamine + Efavirenz Contraindicada
- Dihydroergotamine + Eletriptan Contraindicada
Perguntas frequentes
Can I take Bromocriptine with Dihydroergotamine?
MediHelp rates the interaction as major. Bromocriptine and Dihydroergotamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs are ergot derivatives with vasoconstrictive activity, so combined use may add to the risk of ergotism, including hypertension, peripheral ischemia and vasospasm. Dihydroergotamine also has serotonergic and adrenergic effects that add to bromocriptine's vascular effects.
How serious is the interaction between Bromocriptine and Dihydroergotamine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use; choose a non-ergot alternative for migraine or for the dopamine agonist indication. If unavoidable, monitor for ischemic symptoms and blood pressure elevation.
What other medicines interact with Bromocriptine?
MediHelp also lists interactions of Bromocriptine with, for example, Amisulpride, Atazanavir, Cobicistat. The full list is on the Bromocriptine page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
