Interações medicamentosas
Butabarbital + Dronabinol
Gravidade: Moderada
Butabarbital and Dronabinol: moderate interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Butabarbital induces hepatic enzymes and may lower dronabinol concentrations, reducing its antiemetic or appetite effect. Both drugs also cause CNS depression, so additive sedation is possible.
O que esta interação significa em palavras simples
Butabarbital and Dronabinol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Barbiturate induction of CYP3A4 and CYP2C9 increases dronabinol clearance, plus additive CNS depression.
O que fazer
Monitor for reduced dronabinol efficacy and increase the dose if needed. Watch for excessive sedation.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Butabarbital e Dronabinol, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 14 dias na web. Sem cartão.
Outras interações de Dronabinol
- Cefotetan + Dronabinol Contraindicada
- Disulfiram + Dronabinol Contraindicada
- Dronabinol + Midazolam intranasal Grave
- Dronabinol + Zuranolone Grave
- Amobarbital + Dronabinol Moderada
- Apalutamide + Dronabinol Moderada
Perguntas frequentes
Can I take Butabarbital with Dronabinol?
MediHelp rates the interaction as moderate. Butabarbital and Dronabinol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Butabarbital induces hepatic enzymes and may lower dronabinol concentrations, reducing its antiemetic or appetite effect. Both drugs also cause CNS depression, so additive sedation is possible.
How serious is the interaction between Butabarbital and Dronabinol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for reduced dronabinol efficacy and increase the dose if needed. Watch for excessive sedation.
What other medicines interact with Dronabinol?
MediHelp also lists interactions of Dronabinol with, for example, Cefotetan, Disulfiram, Midazolam intranasal. The full list is on the Dronabinol page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
