Interações medicamentosas
Caffeine + Ciprofloxacin
Gravidade: Moderada
Caffeine and Ciprofloxacin: moderate interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Ciprofloxacin reduces the clearance of caffeine, prolonging its half-life and raising plasma concentrations. Patients may experience jitteriness, insomnia, tachycardia, palpitations or headache, particularly with high caffeine intake.
O que esta interação significa em palavras simples
Caffeine and Ciprofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Caffeine belongs to Miscellaneous; Ciprofloxacin belongs to Anti Bacterial.
Por que acontece
Ciprofloxacin inhibits CYP1A2, the main enzyme responsible for caffeine metabolism.
O que fazer
Advise patients to limit caffeinated drinks and products during ciprofloxacin therapy. Reassess if symptoms such as palpitations, tremor or insomnia occur.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Caffeine e Ciprofloxacin, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 7 dias na web. Sem cartão.
Outras interações de Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicada
- Ciprofloxacin + Fezolinetant Contraindicada
- Ciprofloxacin + Thioridazine Contraindicada
- Ciprofloxacin + Tizanidine Contraindicada
- Ciprofloxacin + Vandetanib Contraindicada
- Alosetron + Ciprofloxacin Grave
Outras interações de Caffeine
- Caffeine + Ephedrine Grave
- Caffeine + Fezolinetant Grave
- Caffeine + Methylenedioxymethamphetamine Grave
- Caffeine + Selegiline transdermal Grave
- Adenosine + Caffeine Moderada
- Benzphetamine + Caffeine Moderada
Perguntas frequentes
Can I take Caffeine with Ciprofloxacin?
MediHelp rates the interaction as moderate. Caffeine and Ciprofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ciprofloxacin reduces the clearance of caffeine, prolonging its half-life and raising plasma concentrations. Patients may experience jitteriness, insomnia, tachycardia, palpitations or headache, particularly with high caffeine intake.
How serious is the interaction between Caffeine and Ciprofloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to limit caffeinated drinks and products during ciprofloxacin therapy. Reassess if symptoms such as palpitations, tremor or insomnia occur.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
