Interações medicamentosas
Caffeine + Ephedrine
Gravidade: Grave
Caffeine and Ephedrine: major interaction.
Última atualização
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Resumo
Both are stimulants, and combined use increases the risk of tachycardia, hypertension, tremor, anxiety, insomnia and arrhythmia. Such combinations have been used in weight-loss products and have been linked to serious cardiovascular events.
O que esta interação significa em palavras simples
Caffeine and Ephedrine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Caffeine belongs to Miscellaneous; Ephedrine belongs to Cardiovascular.
Por que acontece
Additive sympathomimetic and CNS stimulation (indirect adrenergic release by ephedrine plus adenosine antagonism and phosphodiesterase inhibition by caffeine).
O que fazer
Avoid combined stimulant products and limit caffeine intake during ephedrine use; monitor blood pressure and heart rate, particularly in cardiovascular disease.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Caffeine
- Caffeine + Fezolinetant Grave
- Caffeine + Methylenedioxymethamphetamine Grave
- Caffeine + Selegiline transdermal Grave
- Adenosine + Caffeine Moderada
- Benzphetamine + Caffeine Moderada
- Caffeine + Ciprofloxacin Moderada
Outras interações de Ephedrine
- Ephedrine + Isocarboxazid Contraindicada
- Ephedrine + Phenelzine Contraindicada
- Ephedrine + Procarbazine Contraindicada
- Ephedrine + Rasagiline Contraindicada
- Ephedrine + Selegiline Contraindicada
- Ephedrine + Tranylcypromine Contraindicada
Perguntas frequentes
Can I take Caffeine with Ephedrine?
MediHelp rates the interaction as major. Caffeine and Ephedrine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both are stimulants, and combined use increases the risk of tachycardia, hypertension, tremor, anxiety, insomnia and arrhythmia. Such combinations have been used in weight-loss products and have been linked to serious cardiovascular events.
How serious is the interaction between Caffeine and Ephedrine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combined stimulant products and limit caffeine intake during ephedrine use; monitor blood pressure and heart rate, particularly in cardiovascular disease.
What other medicines interact with Caffeine?
MediHelp also lists interactions of Caffeine with, for example, Fezolinetant, Methylenedioxymethamphetamine, Selegiline transdermal. The full list is on the Caffeine page.
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