Interações medicamentosas
Calcium + Oxytetracycline
Gravidade: Moderada
Calcium and Oxytetracycline: moderate interaction.
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Resumo
Oral calcium markedly reduces the absorption of oxytetracycline, which can lead to subtherapeutic antibiotic levels and treatment failure. Dairy-type calcium sources and supplements both contribute.
O que esta interação significa em palavras simples
Calcium and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium belongs to Gastrointestinal Tract; Oxytetracycline belongs to Anti Bacterial.
Por que acontece
Calcium cations chelate oxytetracycline in the gut, forming non-absorbable complexes.
O que fazer
Take oxytetracycline at least 2 hours before or 4 hours after calcium products. Consider a different antibiotic if calcium cannot be withheld.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Calcium
- Calcium + Ceftriaxone Contraindicada
- Acalabrutinib + Calcium Moderada
- Alendronate + Calcium Moderada
- Atazanavir + Calcium Moderada
- Baloxavir marboxil + Calcium Moderada
- Bendroflumethiazide + Calcium Moderada
Outras interações de Oxytetracycline
- Isotretinoin + Oxytetracycline Contraindicada
- Aluminum hydroxide + Oxytetracycline Moderada
- Ampicillin-sulbactam + Oxytetracycline Moderada
- Ampicillin + Oxytetracycline Moderada
- Atracurium + Oxytetracycline Moderada
- Bismuth subsalicylate + Oxytetracycline Moderada
Perguntas frequentes
Can I take Calcium with Oxytetracycline?
MediHelp rates the interaction as moderate. Calcium and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral calcium markedly reduces the absorption of oxytetracycline, which can lead to subtherapeutic antibiotic levels and treatment failure. Dairy-type calcium sources and supplements both contribute.
How serious is the interaction between Calcium and Oxytetracycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take oxytetracycline at least 2 hours before or 4 hours after calcium products. Consider a different antibiotic if calcium cannot be withheld.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
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