Interações medicamentosas
Bismuth subsalicylate + Oxytetracycline
Gravidade: Moderada
Bismuth subsalicylate and Oxytetracycline: moderate interaction.
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Resumo
Bismuth in oral bismuth subsalicylate can bind oxytetracycline in the gut and reduce its absorption. This may lead to lower antibiotic levels and treatment failure.
O que esta interação significa em palavras simples
Bismuth subsalicylate and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bismuth subsalicylate belongs to Gastrointestinal Tract; Oxytetracycline belongs to Anti Bacterial.
Por que acontece
Chelation of oxytetracycline by bismuth in the gastrointestinal tract reduces absorption.
O que fazer
Separate doses by at least 2 to 3 hours, giving oxytetracycline first, or use an alternative if separation is not feasible.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Bismuth subsalicylate
- Bismuth subsalicylate + Dichlorphenamide Grave
- Bismuth subsalicylate + Warfarin Grave
- Acetylsalicylic acid + Bismuth subsalicylate Moderada
- Amlodipine-benazepril + Bismuth subsalicylate Moderada
- Aspirin / citric acid / sodium bicarbonate + Bismuth subsalicylate Moderada
- Aspirin rectal + Bismuth subsalicylate Moderada
Outras interações de Oxytetracycline
- Isotretinoin + Oxytetracycline Contraindicada
- Aluminum hydroxide + Oxytetracycline Moderada
- Ampicillin-sulbactam + Oxytetracycline Moderada
- Ampicillin + Oxytetracycline Moderada
- Atracurium + Oxytetracycline Moderada
- Calcium carbonate + Oxytetracycline Moderada
Perguntas frequentes
Can I take Bismuth subsalicylate with Oxytetracycline?
MediHelp rates the interaction as moderate. Bismuth subsalicylate and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bismuth in oral bismuth subsalicylate can bind oxytetracycline in the gut and reduce its absorption. This may lead to lower antibiotic levels and treatment failure.
How serious is the interaction between Bismuth subsalicylate and Oxytetracycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by at least 2 to 3 hours, giving oxytetracycline first, or use an alternative if separation is not feasible.
What other medicines interact with Bismuth subsalicylate?
MediHelp also lists interactions of Bismuth subsalicylate with, for example, Dichlorphenamide, Warfarin, Acetylsalicylic acid. The full list is on the Bismuth subsalicylate page.
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