Referência de medicamentos
Oxytetracycline
Oxytetracycline is a medicine in the class anti bacterial. It is used for bacterial conjunctivitis.
- Classe do medicamento: Anti Bacterial
- Indicado para: bacterial conjunctivitis
Última atualização
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O conteúdo clínico desta página está disponível apenas em inglês.
Pontos-chave
- Classe do medicamento
- Anti Bacterial
- Formas farmacêuticas comuns
- cápsula
- Concentrações comuns
- 0.5%, 250 mg, 250 mg/3 ml
- Interações conhecidas
- 29 (Contraindicada: 1 · Moderada: 26 · Leve: 2)
- Nomes comerciais
- 4
- Países e mercados
- 2
Para que é usado
Como funciona
Inhibits bacterial protein synthesis by binding with 30S and possibly 50S ribosomal subunit(s)
Dose habitual em adultos (resumo da bula)
Chronic Bronchitis, Acute Exacerbation (Usual daily dose): 500 mg PO q12hr or 250 mg PO q6hr (ie, 1000 mg/day)
Gravidez e amamentação
- Gravidez
- Unsafe Tetracyclines can stain the baby's teeth and affect bone growth once tooth mineralisation starts (about 15 to 16 weeks), and high doses have caused liver toxicity in pregnant women. Avoid oral or injected oxytetracycline in pregnancy; use a safer antibiotic. Skin or eye use gives little absorption.
- Amamentação
- Safe Labels advise avoiding breastfeeding. LactMed is more reassuring: milk levels are low and milk calcium limits absorption, so short courses are probably acceptable; avoid prolonged or repeated courses. Watch the infant for rash, diarrhoea or thrush.
Efeitos adversos relatados
- Nausea
- Anorexia
- Anemia
- Thrombocytopenia
- Increased BUN (dose-related)
Quem deve ter cuidado
- Absorption is adversely affected by milk, antacids and aluminium, calcium, iron, magnesium and zinc salts.
- Tetracyclines depress plasma prothrombin activity, therefore reduced dosages of concurrent anticoagulants may be required.
- Special care should be taken when treating the elderly.
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Principais interações (29)
- Isotretinoin + Oxytetracycline Contraindicated
- Aluminum hydroxide + Oxytetracycline Moderate
- Ampicillin + Oxytetracycline Moderate
- Ampicillin-sulbactam + Oxytetracycline Moderate
- Atracurium + Oxytetracycline Moderate
- Bismuth subsalicylate + Oxytetracycline Moderate
- Calcium + Oxytetracycline Moderate
- Calcium carbonate + Oxytetracycline Moderate
- Carbonyl iron + Oxytetracycline Moderate
- Cholestyramine + Oxytetracycline Moderate
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
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Outros medicamentos desta classe
Perguntas frequentes
What is Oxytetracycline used for?
Oxytetracycline is a medicine in the class anti bacterial. It is used for Bacterial conjunctivitis, Respiratory tract infections, Sexually transmitted infections, Skin infections, Urinary tract infections.
What side effects have been reported with Oxytetracycline?
Nausea, Anorexia, Anemia, Thrombocytopenia, Increased BUN (dose-related).
Can Oxytetracycline be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Tetracyclines can stain the baby's teeth and affect bone growth once tooth mineralisation starts (about 15 to 16 weeks), and high doses have caused liver toxicity in pregnant women. Avoid oral or injected oxytetracycline in pregnancy; use a safer antibiotic. Skin or eye use gives little absorption. Breastfeeding: Safe. Labels advise avoiding breastfeeding. LactMed is more reassuring: milk levels are low and milk calcium limits absorption, so short courses are probably acceptable; avoid prolonged or repeated courses. Watch the infant for rash, diarrhoea or thrush.
What does Oxytetracycline interact with?
MediHelp lists 29 known interactions for Oxytetracycline. Contraindicated: 1 · Moderate: 26 · Minor: 2. The most serious include Isotretinoin, Aluminum hydroxide, Ampicillin.
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