Interações medicamentosas
Carbamazepine + Ensitrelvir
Gravidade: Contraindicada
Carbamazepine and Ensitrelvir: contraindicated interaction.
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Resumo
Carbamazepine is expected to reduce ensitrelvir concentrations substantially, which may lead to loss of antiviral activity and resistance. Strong CYP3A inducers are contraindicated with ensitrelvir.
O que esta interação significa em palavras simples
Carbamazepine and Ensitrelvir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Carbamazepine belongs to Central Nervous System; Ensitrelvir belongs to Anti Virals.
Por que acontece
Carbamazepine induces CYP3A4, accelerating ensitrelvir metabolism.
O que fazer
Avoid the combination and choose an alternative COVID-19 therapy or a non-inducing antiseizure drug. Do not stop carbamazepine abruptly without specialist advice.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Ensitrelvir
- Apalutamide + Ensitrelvir Contraindicada
- Colchicine + Ensitrelvir Contraindicada
- Ensitrelvir + Enzalutamide Contraindicada
- Ensitrelvir + Eplerenone Contraindicada
- Ensitrelvir + Finerenone Contraindicada
- Ensitrelvir + Ivabradine Contraindicada
Outras interações de Carbamazepine
- Artemether / lumefantrine + Carbamazepine Contraindicada
- Cabotegravir + Carbamazepine Contraindicada
- Carbamazepine + Delamanid Contraindicada
- Carbamazepine + Dienogest / estradiol valerate Contraindicada
- Carbamazepine + Doravirine Contraindicada
- Carbamazepine + Elbasvir / grazoprevir Contraindicada
Perguntas frequentes
Can I take Carbamazepine with Ensitrelvir?
MediHelp rates the interaction as contraindicated. Carbamazepine and Ensitrelvir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Carbamazepine is expected to reduce ensitrelvir concentrations substantially, which may lead to loss of antiviral activity and resistance. Strong CYP3A inducers are contraindicated with ensitrelvir.
How serious is the interaction between Carbamazepine and Ensitrelvir?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and choose an alternative COVID-19 therapy or a non-inducing antiseizure drug. Do not stop carbamazepine abruptly without specialist advice.
What other medicines interact with Ensitrelvir?
MediHelp also lists interactions of Ensitrelvir with, for example, Apalutamide, Colchicine, Enzalutamide. The full list is on the Ensitrelvir page.
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