Interações medicamentosas
Carboprost tromethamine + Oxytocin
Gravidade: Grave
Carboprost tromethamine and Oxytocin: major interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Carboprost and oxytocin both stimulate uterine contraction, and used together their effects are potentiated. This is sometimes done deliberately for postpartum hemorrhage, but it raises the risk of uterine hypertonus and, before delivery, uterine rupture.
O que esta interação significa em palavras simples
Carboprost tromethamine and Oxytocin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Por que acontece
Additive uterotonic effect through prostaglandin F2-alpha receptor and oxytocin receptor stimulation.
O que fazer
Use together only under obstetric supervision with continuous monitoring of uterine tone and fetal status where relevant. Avoid in the antepartum setting unless clearly indicated.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Oxytocin
- Dinoprostone + Oxytocin Grave
- Ephedrine + Oxytocin Grave
- Fexinidazole + Oxytocin Grave
- Givinostat + Oxytocin Grave
- Misoprostol + Oxytocin Grave
- Oxytocin + Phenylephrine Grave
Perguntas frequentes
Can I take Carboprost tromethamine with Oxytocin?
MediHelp rates the interaction as major. Carboprost tromethamine and Oxytocin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Carboprost and oxytocin both stimulate uterine contraction, and used together their effects are potentiated. This is sometimes done deliberately for postpartum hemorrhage, but it raises the risk of uterine hypertonus and, before delivery, uterine rupture.
How serious is the interaction between Carboprost tromethamine and Oxytocin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use together only under obstetric supervision with continuous monitoring of uterine tone and fetal status where relevant. Avoid in the antepartum setting unless clearly indicated.
What other medicines interact with Oxytocin?
MediHelp also lists interactions of Oxytocin with, for example, Dinoprostone, Ephedrine, Fexinidazole. The full list is on the Oxytocin page.
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