Interações medicamentosas
Cefaclor + Warfarin
Gravidade: Moderada
Cefaclor and Warfarin: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Cefaclor has been associated with raised INR and bleeding in patients taking warfarin, based mostly on case reports. The magnitude varies between patients, and acute infection may contribute.
O que esta interação significa em palavras simples
Cefaclor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefaclor belongs to Anti Bacterial; Warfarin belongs to Cardiovascular.
Por que acontece
Not firmly established; possibly reduced gut-derived vitamin K or other effects on warfarin response.
O que fazer
Check INR within a few days of starting cefaclor and again after stopping it. Adjust the warfarin dose according to INR and watch for bleeding.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Cefaclor
- Bcg vaccine live + Cefaclor Moderada
- Cefaclor + Cholera vaccine Moderada
- Cefaclor + Kanamycin Moderada
- Cefaclor + Microbiota Moderada
- Cefaclor + Plazomicin Moderada
- Cefaclor + Sodium picosulfate / magnesium oxide / anhydrous citric acid Moderada
Outras interações de Warfarin
- Defibrotide + Warfarin Contraindicada
- Ketorolac + Warfarin Contraindicada
- Abciximab + Warfarin Grave
- Acetylsalicylic acid + Warfarin Grave
- Adagrasib + Warfarin Grave
- Amiodarone + Warfarin Grave
Perguntas frequentes
Can I take Cefaclor with Warfarin?
MediHelp rates the interaction as moderate. Cefaclor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefaclor has been associated with raised INR and bleeding in patients taking warfarin, based mostly on case reports. The magnitude varies between patients, and acute infection may contribute.
How serious is the interaction between Cefaclor and Warfarin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check INR within a few days of starting cefaclor and again after stopping it. Adjust the warfarin dose according to INR and watch for bleeding.
What other medicines interact with Cefaclor?
MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Cholera vaccine, Kanamycin. The full list is on the Cefaclor page.
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